Arruinar, averiar, descomponer.
Ejemplos (Examples):
Cristina me despichó el libro contándome el final.
Cristina ruined the book for me by telling me the ending.
Nuestros planes para un picnic se despicharon con la tormenta.
Our plans for a picnic this afternoon were ruined by the storm.
Mi trabajo se despichó bajando del bus.
My work was ruined by getting off the bus.